I'm 40 But My Biological Age is 23. Here's How I Did It - Chris Mirabile - YouTube

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23:59:59

Overview

Chris Mirabile, founder and CEO of Novos Labs, discusses his journey to slow down his biological age. He emphasizes the importance of addressing all 12 Hallmarks of Aging simultaneously and shares his personal routine, including diet, exercise, and supplementation. He highlights the effectiveness of Novos Core, a supplement designed to target these hallmarks, and presents research findings supporting its efficacy. Chris also discusses various biomarkers he tracks, including epigenetic clocks, VO2 max, and telomere length, and shares inspiring stories of individuals maintaining high levels of fitness into their later years.

Chris's Journey to Slowing Down Aging
- 🧠
  Chris's interest in health began at a young age, but his perspective shifted after being diagnosed with a brain tumor at 16.
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  Discovering the Hallmarks of Aging paper 10 years ago was a turning point, providing a framework for understanding and addressing aging.
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  Chris realized aging is malleable and that certain actions can slow it down, leading to the development of Novos.
Understanding the Hallmarks of Aging
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  The Hallmarks of Aging are 12 biological mechanisms that contribute to aging, including mitochondrial dysfunction, cellular senescence, and telomere shortening.
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  These hallmarks are interconnected and impact each other's function, leading to an exponential decline in health as we age.
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  Chris advocates for addressing all hallmarks simultaneously for a more comprehensive approach to slowing down aging.
Novos Core and its Research
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  Novos Core is a natural supplement designed to address all 12 Hallmarks of Aging.
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  In vitro studies showed Novos Core reduced DNA damage by up to 77% and reduced senescent cell size comparable to rapamycin.
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  A case study with human participants showed 73% slowed their biological age by an average of 1.5 months per year while taking Novos Core and Boost.
Chris's Longevity Routine
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  Chris follows a mostly eucaloric diet with a 16:8 time-restricted feeding window, emphasizing vegetables, legumes, fish, and limited red meat.
- 🏋️‍♂️
  He exercises six days a week, incorporating weightlifting three days and cardio on the other days, including high-intensity intervals and zone 2 training.
- 😴
  Chris prioritizes sleep quality with a strict sleep routine, using blue-blocking lights, earplugs, and a sleep mask.
Biomarkers and Tracking Progress
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  Chris tracks various biomarkers, including epigenetic clocks (DunedinPACE, YOLO), telomere length, VO2 max, and visceral fat.
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  He also uses Novos's Face Age, an AI-powered facial analysis tool, to assess perceived age and skin health.
- 🏆
  Chris believes in setting ambitious goals and striving to outperform his younger self, drawing inspiration from individuals maintaining high fitness levels in their later years.

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Key moments

Introduction and Chris's Journey
Chris Mirabile is introduced as an entrepreneur and longevity enthusiast.
Chris shares his personal story, starting with his early interest in health and his experience with a brain tumor at 16.
He explains how this experience shifted his focus to disease prevention and longevity.
The Hallmarks of Aging
Chris discusses his discovery of the Hallmarks of Aging paper and its impact on his understanding of aging.
He explains the original nine Hallmarks of Aging, including mitochondrial dysfunction, cellular senescence, loss of proteostasis, and more.
He mentions the three newly added Hallmarks: inflammaging, disabled autophagy, and microbiome dysbiosis.
Novos Core and its Impact
Chris introduces his company, Novos Labs, and its mission to address all Hallmarks of Aging simultaneously.
He explains the rationale behind Novos Core, a natural supplement designed to target all 12 Hallmarks.
He shares promising results from in vitro and in vivo studies, demonstrating Novos Core's effectiveness in reducing DNA damage, cellular senescence, and inflammation.
Rejuvenation Olympics and Biological Age Testing
Chris discusses the Rejuvenation Olympics leaderboard and highlights the success of Novos users in slowing down their biological age.
He emphasizes the importance of using accurate biological age clocks, such as the DunedinPACE clock, and explains why chronological age is not a reliable indicator of health.
Chris's Longevity Routine
Chris outlines his personal longevity routine, including his diet, exercise regimen, sleep habits, and supplement stack.
He emphasizes the importance of a balanced approach, acknowledging that overdoing exercise can be counterproductive.
He shares his belief that Novos Core plays a significant role in his results, but stresses the importance of a healthy lifestyle foundation.
Key Takeaways and Advice
Chris reiterates the importance of understanding that aging is malleable and can be influenced by lifestyle choices.
He encourages viewers to adopt healthy habits, including regular exercise, a balanced diet, and quality sleep.
He shares his personal goal of maintaining youthful health and fitness levels for as long as possible.